Monthly Archives: August 2008

SR University Tour – 20th Oct – 4th Nov – Get Involved

Tom Holder of Speaking of Research (SR), will give presentations, participate in debates and/or meet with student groups over the course of the Monday 20th October to the Tuesday 4th November 2008. The first week (20th-25th) is likely to be spent in or around the state of California, where the issue of animal research remains a hot topic in light of recent attacks on universities within the UC (University of California) system.

It is time students, even those not directly involved in research, weighed in on this important issue. We invite student groups to bring SR to your university to speak (in whatever format of your choosing). The talks will cover Holder’s experiences with animal rights extremism in the UK, why animal research is crucial to the future of medicine, and what we could and should be doing to defend it. This opportunity is not exclusive to student groups to organise, but also toward professors and other faculty wishing to play their part in engaging the campus community on the issue.

To invite Tom to speak at your institution, or to enquire further about ways of going about this, contact us through the request a speaker page.

More details on the tour to be released.

Regards

Tom

Taking a BiTE out of non-Hodgkin’s lymphoma

Non-Hodgkin’s lymphoma (NHL) is a diverse family of cancers that affect a part of the body’s immune system known as the lymphatic system.  In NHL white blood cells become cancerous and develop into tumors at key points in the lymphatic system known as the lymph nodes, before spreading to other tissues.  About 50,000 Americans develop NHL every year, and while effective treatments such as Rituximab are available they don’t work for all patients and every year NHL kills nearly 20,000 people in the USA.

So it’s not surprising that the news that Blinatumomab, a novel treatment developed by the German firm Micromet, has performed very well in early clinical trials has been greeted with enthusiasm by cancer  research charities and the stock market alike.

In the trials (1) published this week in the prestigious journal Science, Blinatumomab was given to 38 NHL patients who had not responded to other treatments. In 7 of these patients tumors were found to have shrunk dramatically while in 4 patients the tumors disappeared completely.  Blinatumomab is the first BiTE antibody to enter clinical trials, and its innovative design combines a portion of an antibody, a protein produced by the immune system that binds to foreign material in the body, that targets the cancer cell with a portion of an antibody that binds to the T-cells of the immune system.  The BiTE antibody directs the T-cell to the cancer cell, which the T-cell then destroys.  Blinatumomab was developed after earlier studies using animal models of NHL had shown that antibodies could direct T-cells to target cancer cells, and it was hoped that the BiTE antibodies would do this more effectively. Of course before it was assessed in human clinical trials the BiTE antibody  Blinatumomab was studied in mouse models of NHL, since it was important to determine that they could target circulating immune cells to the tumors (2).

The contribution of animal research to the development of Blinatumomab was not limited to the evaluation of anti-cancer activity and pre-clinical safety, it was also crucial to manufacturing Blinatumomab itself*. BiTE antibodies are produced by heavily modifying a type of antibody known as a monoclonal antibody that binds very specifically to a particular target in the body. The first step of monoclonal antibody production is the immunization of an animal, usually a rodent, with the protein such as a cancer cell protein to which you wish the antibody to bind.  Animals are required for this step because an immune system is needed to produce the immune cells that recognize the target protein, and humans cannot be used for this process both because they cannot be injected with a disease-bearing agent in order to make antibodies, and because the human body does not produce antibodies to the human proteins that researchers often wish to target. Blood samples containing cells that produce antibodies against the foreign protein are then taken from the animal. These antibody producing cells are fused with a special cancer cell to produce a hybrid cell, or hybridoma, which can be grown almost indefinately in the petri dish and produce a large supply of monoclonal antibodies.  These monoclonal antibodies can then in their turn be modified to produce antibody derived drugs such as Rituximab and Blinatumomab.

We hope that larger trials of Blinatumomab against NHL confirm the results of this early trial, and that it will go on to be a valuable addition to the range of treatments available to fight this deadly disease.

* While hybridoma based monoclonal antibody production methods have been very successful, and are vital to current efforts to develop antibody based medicines, replacement technologies that require far fewer animals are currently being developed.  In the coming decades it is hoped that hybridoma based methods will increasingly be replaced by improving in vitro technologies, for example antibody phage libraries that display vast numbers of human or animal antibody fragments and can be used to identify antibodies specific for a particular target. This is a good example of the 3Rs in practise.

Paul Browne

1) Bargou R. et al. “Tumor regression in cancer patients by very low doses of a T cell-engaging antibody.” Science Volume 321(5891), pages 974-977 (2008).

2) Dreier T. et al. “T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3- bispecific single-chain antibody construct.” J. Immunol. Volume 170(8), pages 4397-4402 (2003)

Report: Animal Rights Conference – Part 4

We come to my final day at the Animal Rights Conference, but it is worth quickly looking back over the last few days.

Part 1 – Looks at AR violence and includes recordings of Camille Hankins (Win Animal Rights – WAR) speaking in support of the grave robbings and arson attacks carried out by animal rights activists.
Part 2 – Looks at AR tactics and includes comments and a video on Matt Rossell’s (In Defense of Animals – IDA) infiltration of Oregon National Primate Research Center (ONPRC).
Part 3 – Looks at AR conspiracies and quotes from (and commentary on) various activists from a variety of animal issues.

So on to Sunday and Vivisection Campaigns. This first session was held by Camille Hankins (WAR), George Guimaraes (VEDDAS) who had run campaigns in Brazil, and Matt Rossell of In Defence of Animals (see Part 2 for my comments on his earlier talks). Rossell talks about his time as an infiltrator at ONPRC and the allegations he brought to the USDA (US Department of Agriculture) against them. He, as usual, fails to mention that the USDA cleared ONPRC of all allegations of mistreatment. He also briefly mentions the rest of their current campaigns, against University of Minnesota, Georgetown University, and UC Davis. After Rossell came Guimaraes, who discussed his campaigns in Brazil – trying to use the law to his advantage. Finally came Hankins, and she had an announcement:
SHAC is back!
(Do they lack attack, or do they pack a smack? They’ll be dressed in black to track the quack in our snack … Ok, I’m done)
Hankins proclaimed that she would be helping to bring back SHAC with new members (preferably ones who aren’t in prison). This was one of the only fresh things in her talk (apparently she’s been wanting to announce her intentions for a while on this front). During the Q&A section it was announced that basic science (as opposed to applied) was “Junk Science” (In the next session Rossell used the phrase “Gee Whiz science”) which shows a huge misunderstanding as to the importance of understanding pathologies – which is crucial if you want to go about treating them.

The second of the Sunday sessions I attended was Effective Tactics for Vivisection, with Hankins and Rossell. Rossell’s talk dealt with much the same things as before, as did Hankins for the most part, although Hankins did make two comments worthy of note (albeit maybe for ridiculous comedy value):
We’re trying to stop the drug companies killing your children” – perhaps they should look at corticosteroids and life support systems for premature babies (developed in rabbits and monkeys respectively) or the Meningitis Vaccine (mice) and Asthma Treatments (rabbits) that both continue to help millions of children worldwide.
The threatening letters directed to HLS (Huntingdon Life Sciences) were “probably written by a GSK [GlaxoSmithKline] employer” – No, sorry Camille, you’ve lost me!

Before leaving I popped to the WAR stall. It was interesting to see that they had bolt cutters for sale (can be used to, say, cut fences open) on the stall.

So I hope you enjoyed my review of the animal rights conference. Keep checking back for more interesting stories relating to animals in science, animal rights activism, and the activities of Speaking of Research.

Cheers

Tom

Report: Animal Rights Conference – Part 3

Welcome to the third part of my report on the Animal Rights Conference 2008, that took part in Washington DC (well Virginia actually, but within the DC Metro system) on 15th-18th August 2008. Check back to read Part 1 and 2.

I was still working my way through the first day of the conference when I left you in Part 2. I had been “discovered” as “the kid from Pro-Test in the UK“, having seen talks from Camille Hankins and Matt Rossell among others. So I entered my next session:

Confronting Corporate Threats. The three speakers were Debra Erenberg (RAN – Rainforest Action Network), Harold Brown (Farm Kind) and Camille Hankins (WAR – Win Animal Rights). Erenberg talked about the problems of dealing with corporate PR in the logging industry. Harold Brown extended this PR-fear to a conspiratorial art form – “These PR companies have taken down governments in Central and South America. They’ve taken down governments folks“. “You don’t fight the corporations head to head, because their big and they’ve got people, they have corporate hitmen that work at government levels“. By the end of his talk he had quit talking about farming and animals, and moved onto a rant against free-market capitalism and globalization. The final speaker was Camille Hankins – if you want more information check out Part 1, where we have recordings of her supporting the actions of grave robbers and arsonists. Hankins spoke about her efforts against HLS, protesting against Andrew Baker, and working to attack their banking links. After making her own complaints against PR companies, Hankins decided to do a bit of PR work of her own by urging fellow activists to rebrand the “Pharmaceutical” industry/companies as the “Drug” industry/companies.

The most interesting part of this session came in the Q and A at the end, when an individual in the audience made the comment:
This whole system of private ownership is rotten to the core. That a few people owning and controlling all the wealth, and the means of making more wealth is totally upside down. … [We need] to link up with all the hundreds of thousands of other groups, and millions of people worldwide, who are fighting corporations and the whole corporate system and working towards a whole new world where all the people own and control everything and share the wealth
This brief foray into aspects of Neo-Marxism gets to the heart of the corporate-government conspiracy theory which becomes required to uphold many of their beliefs. In another talk someone suggested that pharmaceuticals were trying actively not to create cures to cancer because then they wouldn’t be able to sell their other treatments (if a scientist found the ultimate cure to cancer you can be sure he’d find someone to mass-produce it) – it is this kind of belief that requires a massive conspiracy against the activists, and this is perhaps why you find many activists poking their heads up on a multiple left-wing issues.

Saturday 16th August

I can probably sum up the three sessions (Running Campaigns, Engaging Businesses, and Activist Support) in a few words (repetetive and irritating?) by saying that the same conspiracy theories involving government and multi-million dollar corporations were repeated by various speakers (I was waiting for the words “military industrial complex”, but alas the conspiracies never quite stooped to that level). Hankins rambled about the dangers of the police – “Trust me, they are not your friends”, as well as the importance of having good security culture. Activists have become smart, they know that the police are watching them (although they seem surprised at this – some AR activists commit crimes, police fight crime, police watch suspected activists to see if they do crime… ) and thus are developing effective security to combat this – Hankins mentioned how she often wrote physical letters and encrypted her emails, Peter Young always warned people to talk of direct action from a hypotheitcal perspective (his fur farm raids and prison sentence were more of a reality).

I did not stay long enough on Saturday to see “R. Nixon” give a talk on “engaging politicians”, but was left wondering if political espionage would be mentioned. Check back to see the concluding part to my report on the Animal Rights Conference.

Leaflet of the Day – Kicking the Cops Out

I don’t even need to comment on this one, it speaks for itself. It also runs “nicely” alongside their government-police-corporate conspiracy theories. I picked this leaflet up from the ALPO (Animal Liberation North American Press Officeo) stall (manned by spokesman Jerry Vlasak) pictures below.

Kicking the Cops Out

There can be no illusions about the purpose of the police. They are just another instrument of the racist ruling class to keep the rest of society from threatening their power. They are NOT a neutral force and do not exist to protect us. The police are NOT for our benefits. They are tools of the state, essential in keeping power in the hands of white, male, corporate Amerika.

Cheers

Tom

p.s. Check back later this week for Part 4

Report: Animal Rights Conference – Part 2

This is the second part of my report on the animal rights conference. Read Part 1 here.

Discovered! As I stood in line to enter the video room I was recognized by a man called Gary, who knew of my UK activities with Pro-Test. I confirmed his suspicion and we had a quick chat before I entered the video room. Like most activists there Gary was friendly, and we politely debated a few quick points on animal research before going onto the next session.

Abuse of animals in science. This shock-titled session was delivered by Camille Hankins (for more on her read part 1 which includes some of her quotes) and Matt Rossell of In Defense of Animals. The video shown was from Rossell’s undercover infiltration of Oregon National Primate Research Center. Instead of going through a point-counterpoint of the entire video, I will instead reflect upon some of the broad tactics used – many of which can be seen in my post some weeks back on a more recent infiltration.

1. Disingenuous motives. Throughout the presentation Rossell implied that he had applied to ONPRC as a technician with no ulterior motives, had been shocked by what he saw, had tried to “change the system from within”, had failed, and then decided to make tapes. In truth, Rossell had infiltrated other organizations including a laboratory before, making tapes in secret before coming out as a whistle blower. He had neglected to mention his employment with PETA on his application to ONPRC (and well as omitting his college education), and for someone who, supposedly, decided to take video footage as a last resort where other methods failed, he started filming just one month after joining the Psychological Well-Being program (3 months into the job) which gave him an excuse to be filming the animals, which he proceeded to do for the next two years. Suspect motives? Almost certainly!

2. Exaggeration. We see a monkey with a swollen arm, and some footage of a cage with several bent bars while the narrator (Rossell) informs us that monkeys regularly get their hand caught in cages, and the cages have to be cut open. At no other point in any footage do we see another cage with any bent bars. According to veterinarians at Oregon this is a rare occurrence, although most incidents tend to be repeats (like humans, certain monkeys are more prone to repeated mistakes), this would explain why there is a single cage with multiple bent bars. It is not uncommon for AR groups to paint relatively rare occurrences as the status quo.

3. Misinterpretation. We are shown a video of a monkey sucking its penis, later on we see a monkey sucking it’s toes. We are told that this abnormal behavior shows distress in the monkey. In reality, human babies do exactly the same thing with regards to sucking fingers and toes, however they lack the flexibility to able to suck any other part of their body. Excessive sucking is may well be a reaction to the stress of having a camera in its face (see video below).

4. Provocation? We see a group of monkeys huddled inside a corner of an otherwise large enclosure. We are led to believe that the monkeys are normally in this state of distress. What we don’t see is cage bars, why? Because Rossell is physically standing inside the enclosure filming the infant monkeys – no wonder they appear to be scared.

5. What You Don’t See. In the video we never see any footage of the large outdoor enclosures in which MOST of the monkeys are housed. Despite the fact that 77% of the monkeys live in social (2 or more) housing, we only tend to see single housed monkeys (an exception is made for infant monkeys that hug one another). Below we see an example of outdoor housing at ONPRC.

There are many other clever camera tricks, such as filming monkeys while a feeding tray is around (anyone with dogs know they exhibit more “manic” behavior when someone has their food bowl ready), and taking footage in the early morning before cage cleaning. These techniques are designed to decieve the viewer as to the conditions in ONPRC. We are never told of th result of the USDA inspection – Oregon were cleared of all allegations of abuse, with only a few minor proposals for improvements (all of which were acted upon), this can be seen in the USDA report.

The raw footage shown to the USDA often has the “context” of Rossell’s videos. In the below video we can clearly see Rossell being the cause of stress to the animal, and yet only the final reaction makes his presentation – as an example of stress from being caged!

Camille then briefly spoke, backing up a handful of Rossell’s points. She informed us of the existence of “better, faster, cheaper alternatives” – but neglected to tell us what they are. I would somewhat guess she is making some of the common mistakes in her understanding of “replacement” methods – of which you can read more about.

After the talk Gary (who had worked out who I was) introduced me to Matt Rossell, and we engaged in a debate for 15 minutes on the merits and demerits of animal research. Rossell is very well spoken, he comes across as dedicated in his beliefs and actions, which his repeated commitment to undercover work confirms. I said I was writing something on the conference, and he asked if he could reply to any comments I made – I accepted. Before writing this blog post I phoned Rossell and asked him about the 5 issues written above. I have addressed his replies at the bottom of this post.

Being as this post is longer than I expected – I will finish it here – look out for the next blog post where we discuss confronting corporate threats, as well as some of the presentations given during the rest of the conference.

Leaflet of the Day – Staples must cut ties to HLS
Staples: How can they be so callous knowing beagle puppies will continue to be killed by a firm they suppy

Hopefully Staples are well aware of the important medical research going on at HLS and are more than glad to be providing office equipment for them. Perhaps the person who made the leaflet misunderstood the intended use of the paperclips and staples which are sent to HLS.

Cheers

Tom


Rossell’s counter-claims

On Disingenuous Motives, Rossell said he did not initially intend to be going as an infiltrator, but when he saw the monkeys he decided to (somewhat different to what he said at the presentation). However with him giving interviews such as this (click link to read), one begins to suspect it was a motive all along.

On Exaggeration, Rossell agreed that such cases were rare, and tended to be repeat offenders – however he seemed shocked that it had to happen 2-3 times before mesh wire was put in to prevent future occurrences. Most people and animals learn from their mistakes. Some monkeys who get their arms stuck will never do it again – no wonder ONPRC does not put in mesh after one incident. Rossell then said that sometimes an animal’s cage that he had installed mesh on, was not returned to the right animal after being taken for cleaning, and that when an animal was stuck the technicians would use lube as well as tugging the monkey before resorting to bending the cage – as if the monkeys were worth nothing. Interestingly, as a technician himself, it was the job of Rossell and others to ensure the right cage was returned to the right monkey. It also stands to reason that if a monkey get his hand through the bars, it may well be able to get it out with a little help (lube, a little force), and that bending the bars should only be used if the limb is well and truly stuck (anyone who has got a finger stuck in a bottle probably knows they prefer to riggle it out with a little discomfort, than to break the bottle).

On Misinterpretation. Rossell asserted that the monkeys were definitely showing signs of stress and that was the reason for the extent of the sucking behavior. We can probably agree that there is some stress related to an animal recently weaned off its mother, but to say they were displaying neurotic behavior from massive stress is probably taking it to far. We must also consider the effect of the camera in the stress reaction (see video above). In the constant effort to improve their own standards, ONPRC have increased the weaning age from 6 months to one year.

On Provocation. Rossell admitted standing in the cage, which he was cleaning, but said that he did not provoke the monkey – that they were frightened and stressed from being separate from their mother. He did then go on to saying he had a hose at the time and said that he had the water on, although was not spraying it. Whether or not Rossell intended to frighten the monkeys, ti does seem his presense to close may be the reason the animals are scared (No one would deny that infant macaques are more prone to temporary fear than an adult – this is the process of growing up.

On What You Don’t See. Rossell explained he only filmed the “dark side” of ONPRC because he was there to give one side – animal abuse at ONPRC. This is a fair point, yet at no point in his presentation did he attempt to explain that most monkeys were in outdoor enclosures.

Rossell had the advantage of knowing the facility and its schedules. If a nurse was to run an expose on her hospital, she would know where to look and which wards to film. In any primate facility (even in the wild) some animals will hurt themselves. Some animals will be undergoing painful experiments (7% of experiments involve some degree of pain that is not alleviated becauise it may affect the experiment egatively). Being as Rossell’s job included spotting distressed monkeys, he was in a position to film them before telling a veterinarian.

Report: Animal Rights Conference – Part 1

For the rest of this week I shall be blogging my thoughts and comments on the Animal Rights Conference, that was held Friday 15th – Sunday 17th August 2008 (the conference actually started on Thursday and finishes on Monday, but I attended the main 3 days).

Friday 15th August, I headed to the Hilton Mark Center in Alexandria to attend the animal rights conference. Far from infiltrating the conference under any false pretenses I chose to sign in under my real name, and although not actively advertising myself and my organization (It’s their conference and I was not there to disrupt it).

Exhibitors and speakers ranged across animal rights issues, from production agriculture to veganism to medical research and more. The first talk that caught my interest was “Applying Direction Action” by Jonny Vasic (Sea Shepherd Conservation Society), Steve Hindi (SHARK – Showing Animals Respect and Kindness … SARK surely?) and Camille Hankins (Win Animal Rights – W.A.R.). Hankins was heavily involved in the campaigns against Huntingdon Life Sciences, as well as being one of the spokesmen for the North American Animal Liberation Press Office (ALPO) which publicizes the violent activities of the Animal Liberation Front (ALF) and Animal Rights Militia (ARM).

Applying Direct Action was an interesting talk since both Vasic and Hindi’s organizations’ claim to stand against violence (arson, bombs, home invasions), whereas Hankins was quite happy to support the more extreme activities of the ALF and ARM. Hankins talked about her part in the campaigns against HLS (in particular in keeping them off the New York Stock Exchange – however HLS has since been listed) and urged others to join in on direct action. Talking more about acceptable forms of direct action, Hankins offered her opinions on two particular incidents.
On the arson attacks on DHL vans – “We drove up to this parking lot, and there were three lorries that had been firebombed, that were in ashes. And you know what, I have to tell you I was excited, I cheered.”
On the grave robbery of Gladys Hammond“I didn’t have a problem with that, besides the person was dead. Nobody got hurt. Except the people that lost the body for a couple of years did.”
[Click on either quote to get the full audio clip (mp3 format) to play in your browser. Audio from official conference recordings]

It seems Hankins may have taken it too far, as the crowd applause after the support of the grave robbing was sporadic at best. Given that this incidents, and other incidents like this, brought the condemnation of non-violent animal rights groups (and rightfully so) who tried to distance themselves from this fringe element, Hankins decided to remind the room that condemning such actions is “betraying our fellow activists.” She finished her talk by confirming her commitment to shutting down HLS by “any means necessary.”

To write off individuals like Hankins as an animal rights nutjob is to forget that she is a powerful and energetic speaker, who’s experiences, advice and encouragement has nurtured many animal rights activists into, sadly, becoming animal rights extremists. Most activists at the convention (or those I heard and spoke to) were genuinely caring and pleasant individuals who are often wrongly tainted by the activities of the extemist elements that exist on the fringe of the movement. Activists such as Hankins do her movement no favors, however she appears to see such criticism from her own movement as betrayal rather than advice.

Leaflet of the day – “Things You Didn’t Know About Animal Testing…”

This was a small leaflet I picked up at an exhibit stand, which included some of the following “facts”.

1. In the US alone, over 87,000 dogs, 20,000 cats and 62,315 non-human primates were used for research in 2006
- They choose an anti-viv website as a source, and seemingly the reason they chose not to use the actual facts from the USDA is because they’ve exaggerated the number of dogs by over 20,000.

2. No law requires that cosmetics and household products be tested on animals
- This is just plain wrong. Any novel cosmetic product in the US MUST be tested on animals, however one can use previously animal-tested chemicals to put new cosmetics on the shelf.

3. At least 450 methods exist with which we can replace animal experiments.
- The truth of the issue can be read in the bad science section.
“This is nonsense, these are techniques used alongside animal research. Only about 10% of medical research involves animals. From time to time non-animal techniques do come along that replace animal tests, but their adoption is rarely controversial as they are almost invariably cheaper and quicker. The vast majority of scientists who undertake animal experiments also use non-animal methods, it is a case of using the appropriate technique for the question being asked. Of course new animal techniques, such as transgenic animals, are regularly developed so the situation is very fluid.”

Keep reading for the rest of my report on the animal rights conference.

Cheers

Tom

Mice aid development of new weapon against HIV

For the past 25 years scientists have sought to develop treatments for HIV, the virus which causes AIDS.  They have had notable successes in that time, particularly with the development of highly active antiretroviral therapy (HAART) which combines several drugs in a potent antiviral cocktail.  Unfortunately HAART does not cure HIV infection, and in many  patients HIV eventually evolves resistance to the drugs. Scientists are therefor constantly working on developing new treatments that can stop HIV progressing to AIDS, and ultimately aim to identify treatments that can eliminate HIV infection altogether.

In the past few years some scientists have explored the potential of small interfering RNAs (siRNAs) in combatting HIV.  The siRNAs work by preventing a virus gene from producing its protein product, thereby preventing the gene from doing its job, and studies done using human cells in petri dishes have shown that siRNAs can block HIV infection.  The problem is that scientists needed a way to target the siRNAs to the T-cells of the immune system which are infected with HIV.
In a paper published online in Cell this week (1) Dr. Premlata Shankar and colleagues describe how they developed a way of targeting the siRNA to the T-cells by using a modified antibody specific for a protein expressed on the surface of those T-cells.  Scientific American discuss this work, while a more detailed discussion can be found at here.

A key part of Dr. Shankar’s work was the development and use of a mouse model of HIV to assess whether the correct cells in the body were being targeted by the modified antibodies.  Mice don’t normally become infected with HIV, but by genetically modifying mice so that own immune system do not develop and then transplanting human umbilical cord stem cells into the mice they were able to produce mice with “humanized” immune systems.  These mice can be infected by HIV and eventually develop an AIDS like illness.  Dr. Shankar’s team found that they could deliver the siRNA’s to the T-cells specifically and block HIV infection the depletion of T-cells that is a hallmark of HIV infection, all without causing any harm to the cells of the immune system.

It is important to note that this is not a cure, several types of cell apart from T-cells are infected by HIV so antibodies that target those other cells will also need to be developed and evaluated.  Still this is excellent news and if further testing indicates that it is safe it may well translate into a treatment for human HIV patients that can be used along side HAART.

Cheers
Paul

1)  Kumar P. et al. “T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice” Cell Online 2008 DOI: 10.1016/j.cell.2008.06.034

Speaking of Research in UC Davis – A Review

On Friday 8th August I visited the California National Primate Research Center at UC Davis. The talk was well received with many leaflets about getting involved in Speaking of Research being taken by the audience afterwards.

I had the pleasure of taking a tour round the Primate Center, where I was impressed by the lengths the animal care staff had gone to provide enrichment for its Rhesus monkeys. Monkeys have bars to swing on, platforms to sit on out of the sun, and many playmates (50+) in each of the outdoor pens.

At 2:30pm I had the pleasure of being interviewed on the Capital Public Radio’s “Insight” show hosted by Jeffrey Callison. The interview can be downloaded here. We discussed issues of extremism, medical benefits, and the UK’s Pro-Test movement.

Cheers

Tom