Cancer Stem Cells: Mouse studies lead to paradigm shift in cancer research

For the past 15 years one of the most intriguing ideas in cancer research has been that the growth and spread of most – if not all – cancers is driven by cancer stem cells. The hypothesis is that only a tiny proportion of cancer cells, cancer stem cells, have the stem cell-like ability to … Continue reading Cancer Stem Cells: Mouse studies lead to paradigm shift in cancer research

Mice help scientists to understand the cancer genome

Yesterday I wrote about how studies carried out using genetically modified mice had enabled scientists to understand the role of the protein BLyS in the disease lupus, leading to the development of a new treatment, and last year I looked at how such studies were helping scientists to identify key genes that are involved in … Continue reading Mice help scientists to understand the cancer genome