Last Monday the Muscular Dystrophy Campaign announced that the antisense oligonucleotide drug AVI-4658 had performed well in its second clinical trial in 19 boys with Duchenne Muscular Dystrophy (DMD). DMD is one of the most common hereditary disorders affecting the skeletomuscular system, and which results in progressive muscle degeneration, difficulty in walking and breathing, and … Continue reading Promising clinical trial result for exon skipping in Duchenne Muscular Dystrophy
Tag: morpholino
A shield against the nightmare: Ebola virus vaccine success
There must be few diseases that can conjure up images of horror the way Ebola virus can. Since it was first identified in Zaire (now the Democratic Republic of the Congo) in the mid-1970’s there have been several outbreaks that have left hundreds of people dead, but it is the potential for far worse outbreaks … Continue reading A shield against the nightmare: Ebola virus vaccine success
Finding animal research in medical news
One of the things that often strikes me when reading about medical advances or clinical trials is how variable the reporting of basic and applied research, including animal research, that underpins the clinical research is. In some cases it is discussed in some depth, but far too often it is either skimmed over or not … Continue reading Finding animal research in medical news
Speaking of Research 