A pig model of cystic fibrosis

Cystic fibrosis is one of the most commonly inherited diseases, affecting about one in every four thousand children born in the USA, and is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene produces a channel that allows the transport of chloride ions across membranes in the body, and … Continue reading A pig model of cystic fibrosis

Update of the Guide for the Care and Use of Laboratory Animals

In a continuing effort to improve the conditions for animals in research, the Institute for Laboratory Animal Research (ILAR) has initiated an update to the 1996 version of the Guide for the Care and Use of Laboratory Animals (commonly known as the Guide). The Guide is not only the basis for AAALAC International accreditation, but … Continue reading Update of the Guide for the Care and Use of Laboratory Animals

Lasker awards highlight the importance of animal models

Every September the Lasker Foundation announces the names of those scientists who will receive awards for their outstanding contribution to fighting disease, and over time these prestigious awards have gained a reputation as "America's Nobels."  Many past awards have been awarded to scientists whose research depended on the use of animals, and this years awards … Continue reading Lasker awards highlight the importance of animal models

Changing cellular career paths.

Every year over 13,000 young people are diagnosed with type 1 diabetes, an autoimmune disease where the bodies own defense system turns on the beta cells of the pancreas that produce insulin.  While the development of insulin therapy has enabled many  type I diabetics to live relatively normal lives there is as yet no cure … Continue reading Changing cellular career paths.