Research with mice paves the way for injectable skin cancer treatment

February 11th 2021 Drug delivery with bioadhesive nanoparticles shows exceptional promise. One in five people in the U.S. will develop skin cancer in their lifetime, with the most common type of malignant skin cancer, squamous cell carcinoma or SCC, killing 10,000 people each year1,2. Cases of skin cancer are steadily rising, and in fact, skin … Continue reading Research with mice paves the way for injectable skin cancer treatment

SYR: Animal Research and MS

This is the first post in the "Speaking of Your Research" series of posts. This post is by Dr Nicole Kerlero de Rosbo, who stood up in front of hundreds of people at the first Pro-Test Italia rally and explained why animal research would continue to be an important part of research in multiple sclerosis. … Continue reading SYR: Animal Research and MS

Natural Antibiotic Casts a Net Against Bacteria

A "natural antibiotic" protects the body against bacteria by tangling them in a net, not poking holes in them, UC Davis researchers have found. Experiments with genetically-modified, or transgenic mice were crucial to the discovery, along with cell cultures, biochemistry and sophisticated studies of how small proteins assemble together. It's an entirely new mechanism of … Continue reading Natural Antibiotic Casts a Net Against Bacteria

Synergy

A claim frequently made by animal rights activists is that by paying for animal research charities and other funding bodies are diverting money from other areas such as clinical research. However the reality is that clinical and animal scientists work together to understand what is going wrong in disease and to illuminate previously unknown aspects … Continue reading Synergy

Shedding some light on the dark side of stem cells

In recent weeks we have discussed the potential of stem cells in developing new therapies, but stem cells also have a more sinister side.  Over the past decade scientists have become increasingly interested in the possibility that in many, perhaps most, cancers there is a small population of cells that are the only tumour cells … Continue reading Shedding some light on the dark side of stem cells

A pig model of cystic fibrosis

Cystic fibrosis is one of the most commonly inherited diseases, affecting about one in every four thousand children born in the USA, and is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene produces a channel that allows the transport of chloride ions across membranes in the body, and … Continue reading A pig model of cystic fibrosis