Mice uncover the secrets of Congenital Heart Defect

Every time your heart beats it pumps blood through the pulmonary artery and into your lungs where it soaks up oxygen before bring returned via the pulmonary vein to the heart, where the next beat pumps it out through the aorta and on to provide oxygen to all the tissues of your body.  All this … Continue reading Mice uncover the secrets of Congenital Heart Defect

University Leadership and Animal Research: A Dean’s perspective

I am a former NIH program manager and have been a research dean for almost 20 years.  I first had to deal with the effects of animal activism on research in 1984, when I was at NIH, and have worked on the issue ever since through my role at NIH, my scientific societies and my … Continue reading University Leadership and Animal Research: A Dean’s perspective

OSU President Yet to Explain Decision to Cancel Primate Project

The rapidly growing controversy over Oklahoma State University’s President Burns Hargis decision to cancel a research project has attracted national attention for a number of reasons.  The November 30th Daily Oklahoman report on Hargis’ decision has ignited discussion and calls for both reversal of the decision and accountability in addressing the many questions that have … Continue reading OSU President Yet to Explain Decision to Cancel Primate Project

Oklahoma University President Interferes with Federally Funded Health Research

  Call for Support of Oklahoma Scientists and Research Programs   Speaking of Research, along with scientists and others across the country, were appalled to learn yesterday that Oklahoma State University’s President cancelled a research project for which his university had already accepted federal funding and which had been approved at all levels of review … Continue reading Oklahoma University President Interferes with Federally Funded Health Research

A look at responsible research with monkeys

At the last Pro-Test for Science rally (then UCLA Pro-Test) I was trying to explain opponents of research that the images of bleeding monkeys shown in their signs were either from decades ago or from other countries, not the US or the European Union, and certainly not representative of research at the University of California. … Continue reading A look at responsible research with monkeys

Gene therapy on the brain

Hot on the heels of last weeks report of the successful use of gene therapy to treat the eye disease Leber’s congenital amaurosis comes a report that scientists lead by Nathalie Cartier and Patrick Aubourg of the French National Institute for Health and Medical Research have combined gene therapy and stem cell medicine to successfully … Continue reading Gene therapy on the brain

Gene therapy for blindness – when dogged determination pays off!

Leber's congenital amaurosis is a progressive disorder that affects about 3,000 Americans, and hundreds of thousands worldwide, and causes a progressive loss of vision that usually results in blindness. The disease, for which there has until now been no effective treatment, is caused by a mutation in the encoding RPE65, an enzyme which is crucial … Continue reading Gene therapy for blindness – when dogged determination pays off!

So, what have we learned about the Brain?

One hundred years ago we knew almost nothing about the brain.  By all measures, neuroscience is really a field in its early infancy. What have we learned in this short period?  How has animals work contributed? Follow Charlie Rose in a his new “Brain Series” as he covers and celebrate the accomplishments of neuroscientists. In … Continue reading So, what have we learned about the Brain?