The Importance of Animal Experimentation and the mdx mouse model to Muscular Dystrophy Research

Louise Richardson is a PhD student at the University of Leeds. Her work focuses on satellite cells and their contribution to skeletal muscle plasticity, with a view to understanding more about genetic muscle disorders and sarcopenia. She has a Masters of Research with an in-vivo specialisation and a BSc. in Human Anatomy. In this post … Continue reading The Importance of Animal Experimentation and the mdx mouse model to Muscular Dystrophy Research

Mars, Machine Learning, and Mice: How a planetary science spin-off has the potential to improve imaging in animal research

Dr. Paul Tar is a research associate at the University of Manchester. In this guest post Paul explains the interdisciplinary journey taken between his PhD, in the analysis of planetary images, and current research post, in cancer studies. In this post he discusses how machine learning used to make measurements in space can also be … Continue reading Mars, Machine Learning, and Mice: How a planetary science spin-off has the potential to improve imaging in animal research

Seeing the Light: Managing Neuropathic Pain with Phototoxicity

Neuropathic pain is a chronic condition that affects an estimated 6.9-10.0% of people and usually arises from damage to the nervous system. The mechanisms underlying neuropathic pain are complex and different than those causing acute pain and inflammatory pain, thus requiring a different therapeutic approach. Unfortunately, the majority of people with neuropathic pain do not … Continue reading Seeing the Light: Managing Neuropathic Pain with Phototoxicity

Does size matter? Evaluating the space requirements for laboratory mice.

Mice are the most commonly used laboratory animal – comprising approximately 70% of all animals used for research. Despite their widespread use, surprisingly little is known about how the behavioural biology of mice relates to the social and physical conditions of the laboratory environment. A team of researchers, from the Division of Animal Welfare at … Continue reading Does size matter? Evaluating the space requirements for laboratory mice.

Openness by the numbers: Ten universities conduct one third of all UK animal research

The ten British universities which conduct the most animal research have come together to proactively publicise their exact figures to the public and media. The press release by the ten institutions was coordinated by Understanding Animal Research. It is the second time that universities have come together to publicise their numbers. Of the 46 universities … Continue reading Openness by the numbers: Ten universities conduct one third of all UK animal research

Of Mice and Mammaries, Part 4: From animal models to human therapies

In light of Breast Cancer Awareness Month, Justin Varholick traces how mice have helped breast cancer research over the past century. Over the past month, in Parts 1, 2, and 3 of this series, he discussed how scientists began studying mammary tumors in mice and how they have advanced their study to better understand human … Continue reading Of Mice and Mammaries, Part 4: From animal models to human therapies

Of Mice and Mammaries, Part 3: Modelling Human Breast Cancer

In light of Breast Cancer Awareness Month, Justin Varholick traces how mice have helped breast cancer research over the past century. In the third post of this 4-part series, we look at advances made from the 1970s to present time and how mice are being used as a model for humans. Over the past two … Continue reading Of Mice and Mammaries, Part 3: Modelling Human Breast Cancer