This is a guest post on the utility of animal models in drug development, misconceptions about animal models, and alternative methods of drug development, by Dale M. Cooper, DVM, MS, Diplomate, American College of Laboratory Animal Medicine. Dr. Cooper has over 20 years of veterinary experience in private practice, and as a laboratory animal veterinarian … Continue reading Guest Post: Predictability and Utility of Animal Models
Dr. Swapna Mohan is a post-doctoral fellow at the National Institutes of Health. She is a veterinarian and recently completed her PhD in Molecular Physiology from Cornell University, NY. She is interested in maximizing the use of animals in research and agriculture, while keeping with humane and ethical standards. The FDA has approved “female Viagra” … Continue reading Guest Post: Sex, Drugs and the Validity of the Animal Model
The following guest post is by Dr Rosie Morland. Dr Morland recently completed a PhD in neuroscience and pain studies at Imperial College, London, and she has a particular interest in how animal models can help increase understanding of complex pain disorders. You can read more from her on her blog. The article was originally … Continue reading Guest Post: CRPS Animal Models Explained
The following guest post is from Jeff Weiner, a Professor in the Department of Physiology and Pharmacology at Wake Forest School of Medicine. Dr. Weiner is the Director of an NIH-funded translational research grant that employs rodent, monkey and human models to study the neurobiological substrates that contribute to alcohol addiction vulnerability. He is also … Continue reading Why is alcohol research with nonhuman animals essential?
It's January, and across the country millions of people have promised themselves that they will eat less, loose weight and become healthier. But why do some people eat more than others? No matter what they try there seems to be no way to stop their overeating. Public education is a powerful tool to combat some … Continue reading Guest Post: Characterising high fructose corn syrup self-administration in laboratory rats
A second federal agency charged with oversight of animal research has completed a thorough investigation of an animal rights group's complaints about sound localization research with cats at the University of Wisconsin. Summary of the result: “there was no direct noncompliance with the PHS Policy or serious deviation from the provisions of the Guide for … Continue reading Animal welfare inspectors clear UW-Madison cat research of PETA allegations, important hearing research continues
Unfortunately, the “how” and “why” of the research process is of much less interest, and receives far less attention, than the “what did they find?!” part of research. The latter is what you’ll see—if we’re lucky from the science outreach perspective— on television, in the science and popular media, Facebook, Twitter, and conversations world-wide. Meanwhile, … Continue reading A Closer Look at How Animal Research Progresses from Idea to Study
“Is it nature or nurture?” “How does that work? How can social experiences actually change someone’s brain?” “So early experiences matter, but how much? Is it reversible? How long does it last? Is there a way to change the course?” All of these are popular questions that I hear from students, community members, clinicians, and … Continue reading Bridging the gap: Monkey studies shed light on nature, nurture, and how experiences get under the skin