Why study whiskers in mice? Humans don’t have whiskers

Sometimes an exciting research finding is quickly attacked by the internet because it was done #InMice. But some of the most exciting discoveries have resulted from studies  #InMice. And some things #InMice, like their lungs, hearts, livers, and bladders, are surprisingly more similar to humans than we may assume. It’s also just fun to learn … Continue reading Why study whiskers in mice? Humans don’t have whiskers

Evergreen: Statistics out of context, predictability, and utility of animal models

March 18th 2022 In a recent letter to the US National Institutions of Health (NIH) , Congressman Ted W. Lieu (D-CA) and Congresswoman Nancy Mace (R-SC) called for the NIH “to discontinue animal experiments and find alternatives to animal testing.” They write: “As Members of Congress, we are concerned the National Institutes of Health (NIH) … Continue reading Evergreen: Statistics out of context, predictability, and utility of animal models

#Evergreen: Sex, Drugs and the Validity of the Animal Model

April 16th 2021 We have continued to highlight the valuable role that #AnimalResearch plays in bringing improvements to quality of life and life saving cures from bench to bedside (e.g., here, here, here). We also have continued to emphasize the process of science as a self-correcting endeavor, and that this is a feature not a … Continue reading #Evergreen: Sex, Drugs and the Validity of the Animal Model

#Evergreen: Predictability and Utility of Animal Models

March 26th 2021 Yesterday we highlighted one of the myths that those opposed to #AnimalResearch often spend their time propagating—that #AnimalResearch is only performed in benefit to humans—usually alongside the myth that #AnimalResearch fails to translate to humans. It is thus timely to highlight another of our posts debunking another prevalent and sensational claim—that 99% of drugs … Continue reading #Evergreen: Predictability and Utility of Animal Models

Guest Post: Predictability and Utility of Animal Models

This is a guest post on the utility of animal models in drug development, misconceptions about animal models, and alternative methods of drug development, by Dale M. Cooper, DVM, MS, Diplomate, American College of Laboratory Animal Medicine. Dr. Cooper has over 20 years of veterinary experience in private practice, and as a laboratory animal veterinarian … Continue reading Guest Post: Predictability and Utility of Animal Models

Guest Post: Sex, Drugs and the Validity of the Animal Model

Dr. Swapna Mohan is a post-doctoral fellow at the National Institutes of Health. She is a veterinarian and recently completed her PhD in Molecular Physiology from Cornell University, NY. She is interested in maximizing the use of animals in research and agriculture, while keeping with humane and ethical standards. The FDA has approved “female Viagra” … Continue reading Guest Post: Sex, Drugs and the Validity of the Animal Model

Guest Post: CRPS Animal Models Explained

The following guest post is by Dr Rosie Morland. Dr Morland recently completed a PhD in neuroscience and pain studies at Imperial College, London, and she has a particular interest in how animal models can help increase understanding of complex pain disorders. You can read more from her on her blog. The article was originally … Continue reading Guest Post: CRPS Animal Models Explained

Why is alcohol research with nonhuman animals essential?

The following guest post is from Jeff Weiner, a Professor in the Department of Physiology and Pharmacology at Wake Forest School of Medicine.  Dr. Weiner is the Director of an NIH-funded translational research grant that employs rodent, monkey and human models to study the neurobiological substrates that contribute to alcohol addiction vulnerability.  He is also … Continue reading Why is alcohol research with nonhuman animals essential?