Yesterday, NIH and Moderna announced the start of a multi-site, Phase 3 clinical trial of a candidate vaccine for COVID-19. This candidate vaccine uses messenger RNA, or mRNA, a “codebook” that cellular machinery “reads” in order to build proteins. For this candidate vaccine, the mRNA contains instructions for building spike proteins found on the coronavirus, … Continue reading Animal models paved the way for Phase III testing of the COVID-19 vaccine
Recent news indicates that the Ebola virus is spreading throughout the northern region of the Democratic Republic of Congo, including one case in Mbandaka, a city with a population of 1 million. Many people will remember the outbreak in 2014 that led to more than 10,000 deaths in West Africa. In efforts to curb a new outbreak, the … Continue reading Ebola Vaccine, four decades in the making
Welcome to this week’s Research Roundup. These Friday posts aim to inform our readers about the many stories that relate to animal research each week. Do you have an animal research story we should include in next week’s Research Roundup? You can send it to us via our Facebook page or through the contact form … Continue reading Research Roundup: Malaria vaccine, mouse sperm in space, animal welfare prizes, and more!
A recent article in the journal Pediatrics reported that vaccination against human papilloma virus (HPV) resulted in a 64% reduction in infections in girls aged 14-19 (1). The vaccine, Gardasil, came onto market in June of 2006 and protects again four different HPV types: the two most prevalent high-risk viruses, HPV16 and HPV18, and the … Continue reading HPV vaccines and cervical cancer – a success in animals is a success for humans
Today's guest post is by Jordana Lenon, Wisconsin National Primate Research Center and Kathy West, California National Primate Research Center. Researchers at Duke and Tulane take the lead, the National Primate Research Centers provide critical resources and expertise in this first-ever proof of CMV placental transmission in nonhuman primates. Researchers now have a powerful new … Continue reading One step closer to a vaccine for cytomegalovirus: Monkeys transmit CMV the same way as humans
Respiratory syncytial virus (RSV) affects almost two-thirds of babies in their first year of life, and is a leading cause of bronchiolitis and severe respiratory disease in infants, young children, immunocompromised individuals, and the elderly throughout the world. It is a major cause of hospital admission for infants, and results in up to 200,000 deaths … Continue reading Cotton Rats, Calves and Clinical Trials: New RSV vaccine shows great promise.
The current Ebola virus outbreak in Guinea, Sierra Leone and Liberia is a stark reminder on the need for effective therapies and vaccines for this disease, which has claimed the lives of thousands of people in West Africa in a series of outbreaks since the 1970’s. It is not just the human inhabitants of West Africa … Continue reading Ebola virus vaccine developed to protect wild gorillas and chimpanzees
Bacterial meningitis is an infection of the fluid that is found in the spinal cord and surrounding the brain that affects thousands of people – usually children or young people – every year and can result in brain damage, hearing loss, or learning disability. In about 10% of cases the infection is fatal. One of … Continue reading Universal Meningitis B vaccine nears approval by European regulators – thank the mice (and the scientists)!