What is failure?  Shelved cancer treatment becomes first effective AIDS/HIV treatment

April 28, 2022 Allyson J. Bennett, Jeremy D. Bailoo, Sangy Panicker 1964.  Lead scientist, Jerome P. Horwitz, working on new cancer treatments developed azidothymidine in 1964. Their work was funded by the National Cancer Institute (NCI, Grant #’s CY-5943 and CA-02903), one of the institutes within the publicly-funded US National Institutes of Health (NIH).  It … Continue reading What is failure?  Shelved cancer treatment becomes first effective AIDS/HIV treatment

Advances from Animal Research: AIDS and Zika Vaccines Update

April 19th, 2021Professor Christopher Petkov Although we have been focusing on updates on Covid-19 vaccines and their reliance on research with nonhuman animals including primates (as an example post see here), two other developments focusing on treatments for AIDS and Zika fever have caught our eye. These fall under the topic #MPAR, Made Possible by … Continue reading Advances from Animal Research: AIDS and Zika Vaccines Update

Truvada prevents HIV infection in high-risk individuals! A clinical success built on animal research

In the past two weeks we've learned of a major advance in ongoing efforts to halt the spread of  HIV, two separate clinical studies have reported that a daily regimen of a pill called Truvada as a pre-exposure prophylaxis (PrEP) is highly effective in preventing infection in high risk groups. This success is a result … Continue reading Truvada prevents HIV infection in high-risk individuals! A clinical success built on animal research

Remembering a hero of the struggle against HIV/AIDS

December 1st is World AIDS Day, dedicated to raising awareness of the worldwide AIDS pandemic, to support people living with HIV/AIDS and to commemorate those who died. The disease has claimed over 25 million lives.  Worldwide, over 33 million people are now living with HIV/AIDS. This year marks the 30th anniversary of the first report … Continue reading Remembering a hero of the struggle against HIV/AIDS

Mice and macaques pave the way for effective HIV vaccines

There is encouraging news this week on the prospects for an effective vaccine against HIV. A  research team led by Professor Mariano Esteban at the Spanish Superior Scientific Research Council (CSIC) have announced that the vaccine MVA-B elicited a persistent immune response against HIV in  85% of volunteers in a phase 1 clinical trial. MVA-B … Continue reading Mice and macaques pave the way for effective HIV vaccines

Good news on HIV prevention – thanks to animal studies

A once-a-day pill is effective in preventing HIV infection, according to two big new human studies released last week. This could add a preventive pill to the toolkit of HIV prevention, alongside condom use, abstinence, and vaginal microbicides. Of course, these human trials would not have been possible had the drugs not been first shown … Continue reading Good news on HIV prevention – thanks to animal studies

Animal studies point to clinical trial of hypothermia for stroke victims

On Monday Dr Malcolm Macleod, head of experimental neuroscience at the Centre for Clinical Brain Sciences at the University of Edinburgh, joined scientists from the European Stroke Research Network for Hypothermia (EuroHYP) in urging European governments to fund a  trial of moderate hypothermia for the treatment of ischemic stroke victims.  In ischemic stroke the blood … Continue reading Animal studies point to clinical trial of hypothermia for stroke victims

Open Letter to the Justice Department

In recent days, the Justice Department (the moniker of an animal rights terrorist group) sent a letter to my home that contained razor blades and graphic threats to “cut my throat”, and they have openly announced that they sent similar letters to at least one of my trainees. The letter that was sent to my … Continue reading Open Letter to the Justice Department