How mice helped develop a new drug for MS

In the news today there have been reports that laquinimod, a new drug developed to treat multiple sclerosis (MS), has performed well in an early (Phase IIb) (1). An MS patient's immune system attacks their central nervous system, leading to impaired communication in the nervous system and finally to physical and cognitive disability. A key … Continue reading How mice helped develop a new drug for MS

A vaccine against meningitis B?

Newspapers in the UK are buzzing with excitement over news that a new vaccine against meningitis B developed by the Swiss pharmaceuticals firm Novartis has performed well in early clinical trials. http://www.guardian.co.uk/society/2008/may/15/health.medicalresearch http://www.independent.co.uk/life-style/health-and-wellbeing/health-news/meningitis-defeated-at-last-828286.html About 3,000 mostly young people catch meningitis B every year in the USA, of whom about 10% die and 25% suffer lifelong … Continue reading A vaccine against meningitis B?

Animal research behind the headlines

The BBC has reported on calls for the new blood-thinning drug Pradaxa (dabigatran etexilate/BIBR 1048) to be used more widely in patients who are at risk of blood clots following surgery, a serious complication that kills 25,000 patients each year. This drug works be inhibiting the enzyme Thrombin, a key player in clot formation. http://news.bbc.co.uk/1/hi/health/7354818.stmContinue reading Animal research behind the headlines