Heart failure, where the heart is unable to maintain a sufficient blood flow to supply the body’s needs, is a leading cause of death, especially among the over 65’s. Half of all chronic heart failure patients die within four years of diagnosis. It can have a number of causes, for example damage to heart tissue … Continue reading Heart failure breakthrough: animal research paved the way!
It’s just over a decade since the completion of the first working draft of the human genome was announced, and seven years since the publication of the complete sequence, but in that short time the impact of this new knowledge on all areas medical research has been immense. Sequencing the human genome was a huge … Continue reading Mice, rats, and the secrets of the genome.
Tissue engineering, a field that combines cell biology, engineering, and materials science to manufacture tissues - and more recently even whole organs - to replace those lost to injury or illness, must be one of the most exciting areas in modern medicine. Since the earliest reports about a mouse with a human ear growing on … Continue reading How to build a lung
The contributions of animal research to human health are many. In response to blanket statement that animal research “does not work” I wanted to provide three examples of how animal research has directly benefited the health of women and their babies: in-vitro fertilization, oral contraceptives and neonatal intensive care. Do you or any of your … Continue reading Animal Research Benefits Mom and Baby Alike
When we think of the immune system we usually think of the adaptive immune system - the B-cells and T-cells that recognize and destroy specific pathogens – which isn’t surprising since this is the arm of the immune system that vaccines are designed to stimulate. However working alongside the adaptive immune system is the innate … Continue reading Septic shock: Mice show way to a new treatment
One of the things that often strikes me when reading about medical advances or clinical trials is how variable the reporting of basic and applied research, including animal research, that underpins the clinical research is. In some cases it is discussed in some depth, but far too often it is either skimmed over or not … Continue reading Finding animal research in medical news
Back in October I wrote about how animal research has enabled the development of brain cooling as a treatment to reduce brain damage in babies who had suffered oxygen starvation during birth. This is a problem that affects tens of thousands of babies every year, and frequently results in death or long-term disability. Brain cooling … Continue reading A Noble cause: Protecting babies brains with Xenon