Animal research leads to promising results for first clinical trial of stem cell therapy for stroke

The BBC reported yesterday that a small trial of a stem cell therapy developed by the biotech firm Reneuron has produced promising results, with 5 of the 9 patients enrolled in the trial showing unexpected improvements. The improvements were unexpected because the trial was intended to assess the safety of the technique, and the scientists … Continue reading Animal research leads to promising results for first clinical trial of stem cell therapy for stroke

Not Difficult To Grasp

Paralysis can have tremendous negative consequences for a person's quality of life.  In the US alone, there are more than 200 thousand people living with chronic spinal cord injury, which is a cause of immense suffering to them and their families.  The disease generates economic burden for society as well.   Thus, there has been … Continue reading Not Difficult To Grasp

Hypothermia in stroke: EuroHYP moves from rats to man

Earlier today the BBC reported that European Stroke Research Network for Hypothermia (EuroHYP) has announced the launch of a major clinical trial – involving 1,500 patients in 15 centers across Europe – to evaluate whether cooling the body by 2 degrees can reduce the risk of death and disability in ischaemic stroke. The trial, known … Continue reading Hypothermia in stroke: EuroHYP moves from rats to man

How nerve cells reach their niche.

Developmental biology, the study of the processes through which organisms grow and develop, is an area of biomedical research where modal organisms - ranging from the slime mold Dictyostelium  discoideum to the chicken - play a crucial role, and one that has been honoured with several  Nobel Prizes in recent years.  For example, the 1995 … Continue reading How nerve cells reach their niche.

Animal studies point to clinical trial of hypothermia for stroke victims

On Monday Dr Malcolm Macleod, head of experimental neuroscience at the Centre for Clinical Brain Sciences at the University of Edinburgh, joined scientists from the European Stroke Research Network for Hypothermia (EuroHYP) in urging European governments to fund a  trial of moderate hypothermia for the treatment of ischemic stroke victims.  In ischemic stroke the blood … Continue reading Animal studies point to clinical trial of hypothermia for stroke victims