How to build a lung

Tissue engineering, a field that combines cell biology, engineering, and materials science to manufacture tissues - and more recently even whole organs - to replace those lost to injury or illness, must be one of the most exciting areas in modern medicine. Since the earliest reports about a mouse with a human ear growing on … Continue reading How to build a lung

Finding animal research in medical news

One of the things that often strikes me when reading about medical advances or clinical trials is how variable the reporting of basic and applied research, including animal research, that underpins the clinical research is.  In some cases it is discussed in some depth, but far too often it is either skimmed over or not … Continue reading Finding animal research in medical news

A Noble cause: Protecting babies brains with Xenon

Back in October I wrote about how animal research has enabled the development of brain cooling as a treatment to reduce brain damage in babies who had suffered oxygen starvation during birth. This is a problem that affects tens of thousands of babies every year, and frequently results in death or long-term disability. Brain cooling … Continue reading A Noble cause: Protecting babies brains with Xenon

A pig model of cystic fibrosis

Cystic fibrosis is one of the most commonly inherited diseases, affecting about one in every four thousand children born in the USA, and is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene produces a channel that allows the transport of chloride ions across membranes in the body, and … Continue reading A pig model of cystic fibrosis